A Convenient Method for the Synthesis of Alkylsilyl Cyanides Using Potassium or Sodium Cyanide Impregnated on Amberlite XAD Resin
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چکیده
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A practical and convenient method for the synthesis of anesthetic drug thiopental: using thiourea and sodium ethoxide
A general, simple, practical and convenient method has been described for the synthesis of anesthetic drug thiopental using thiourea in the presence of sodium ethoxide. Anesthetic drug of thiopental was prepared in two stages; during the first stage, the alkylation of mthyl cyanoacetate was performed which was then to be followed by cyclization. Alkylation of methyl cyanoacetate which was perfo...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1987
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.60.2257